They recently started allowing users to unlock the Sensation and EVO 3D bootloader through the HTCDev tool, but they are not granting S-off status. which unlocks the ability to flash things like radios and hboot versions.
HTC’s method gives you the ability to flash a modified version of a custom recovery, which will let you flash the files needed to root your phone. Of course you will be able to run apps that require root and have read/write permissions. If that is all you wanted to do than HTC’s method is great.
If you think you want to do more, it might make sense to wait. It is possible that the development community will figure out how to flash ROMs using HTC’s tool, and there might be a chance the boot partition can be flashed. Since HTC has made it impossible to go back after using their tool, you should wait and see what lies ahead.
There are also rumors that HTC will eventually give S-Off status, but that is completely unknown. Stay tuned.